Decomposition and Reconstruction of Protein Sequences: The Problem of Uniqueness and Factorizable Langauge

نویسندگان

  • Xiaoli Shi
  • Huimin Xie
  • Shuyu Zhang
  • Bailin Hao
چکیده

In our attempt to justify the CVTree approach of inferring phylogenetic relationship among bacteria from their complete genomes without using sequence alignment, we encountered the problem of the uniqueness of the reconstruction of a protein sequence from its constituent K-peptides, which has a natural relation to a well-understood problem in graph theory, namely, the number of Eulerian loops in a graph. The existence of finite state automata to recognize the uniqueness of a sequence reconstruction provides us with yet another application of factorizable language, which was elucidated at a previous Dynamics Days Asia Pacific meeting (DDAP1).

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تاریخ انتشار 2007